Clinical Studies

Collagen Science: Clinical Studies

Nearly a century of research has given us a good understanding of the important role collagen plays in skin renewal and repair.

More recently we’ve learned how beneficial collagen supplementation is to the appearance of your skin.

Now Ashieda is proud to add our own Clinical Study to this important research.

Beauty Nectar Clinical Study

  • Location: Beverly Hills, CA USA
  • Year: 2013
  • Study: 10 women between 29 – 60 years were given a drink containing 3023mg of hydrologized collagen with a proprietary amount of anti oxidants every day for 12 weeks.
  • Results: increases in skin hydration, firmness, smoothness, and suppleness, and decreases in the appearance of fine lines and pores. Subjects also reported that their skin looked more nourished, plump, and bright with improved skin tone.

Previous Clinical Studies

Souken Study

    • Location: Tokyo, Japan
    • Year: 2008
    • Study: 33 women between 40 – 60 years were given a drink containing 10g of hydrologized collagen every day for two months.
    • Results: After two months, 91% saw a significant increase in skin resilience and hydration.
    • Dermiscan Study


  • Location: Lyon, France
  • Year: 2009
  • Study: Women between 35 – 55 years were given a drink containing 10g of hydrologized collagen every day for 12 weeks.
  • Results: After 12 weeks there was 41% less furrowing, less wrinkles, more resilience and more hydration.

General Consensus

Skin becomes firmer with better suppleness, hydration, resilience and strength when supplementing your diet with a drink containing hydrologized collagen.

Water content in the skin tissue (a fancy way to say hyrdation) is related to skin smoothness, suppleness and reducing furrows and wrinkles.

Collagen Science References

Collagen Degradation in Aged/Photodamaged Skin in Vivo and After Exposure to Matrix Metalloproteinase-1 in Vitro
S.E. Fligiel, J. Varani, S.C. Datta, S. Kang, G.J. Fisher, J.J. Voorhees
The Journal of Investigative Dermatology Vol. 120, No. 5, Pg. 842-8 (2003)

Collagen Synthesis in Human Musculoskeletal Tissues and Skin
J.A. Babraj, D.J.R. Cuthbertson, K. Smith, H. Langberg, B. Miller, M.R. Krogsgaard, M. Kjaer, and M.J. Rennie
American Journal of Physiology Endocrinology and Metabolism Vol. 289 No. 5 Pg. 864-9 (2005)

Modulation of Skin Collagen Metabolism in Aged and Photoaged Human Skin in Vivo
J.H. Chung, J.Y. Seo, H.R. Choi, M.K. Lee, C.S Youn, H.C. Eun
Biomedical Gerontology Vol. 25, No. 1, Pg. 26 (2001)

Chemical, Biochemical, Functional, and Nutritional Characteristics of Collagen in Food Systems
A. Asghar, R.L. Henrickson
Advances in Food Research vol 28 p 231 (1982)

Oral Administration of 14C Labeled Gelatin Hydrolysate Leads to an Accumulation of Radioactivity in Cartilage of Mice
The Journal of Nutrition Vol. 129, No. 10, Pg. 1891 (1999)

Chemotactic Attraction of Human Fibroblasts to Type I, II, and III Collagens and Collagen-derived Peptides
A.E. Postlethwaite, J.M. Seyer, A.H. Kang
Proceedings Of The National Acadamy Of Sciences Vol. 75, No. 20, Pg. 871 (1978)

A Breakfast with Alpha-lactalbumin, Gelatin, or Gelatin + TRP Lowers Energy Intake at Lunch Compared with a Breakfast with Casein, Soy, Whey, or Whey-GMP
M.A. Veldhorst, A.G. Nieuwenhuizen, A. Hochstenbach-Waelen, K.R. Westerterp, M.P. Engelen, R.J. Brummer, N.E. Deutz, M.S. Westerterp-Plantenga
Clinical Nutrition Vol 28, No. 2, Pg. 147-55 (2009)

Effects of Whey and Fortified Collagen Hydrolysate Protein Supplements on Nitrogen Balance and Body Composition in Older Women
N.P Hays, H. Kim, A.M. Wells, O. Kajkenova, W.J. Evans
Journal of The American Dietetic Association Vol. 109, No. 6, Pg. 1082-7 (2009)

Textbook of Medical Physiology
Arthur C. Guyton, John E. Hall – W.B. Saunders Co (1996)

The Arthritis Cure: The Medical Miracle That Can Halt, Reverse, And May Even Cure Osteoarthritis
Jason Theodosakis – St. Martin’s Griffin (1997)

Effects of Oral Ingestion of Collagen Peptide on the Skin.
Y. Koyama, A. Sakashita, K. Kuwaba, M. Kusubata
Fragrance Journal Vol. 34, No. 6, Pg. 82-85 (2006)

Pharmacokinetics of glucosamine in man
Setnikar I, Palumbo R, Canali S, Zanolo G.
Rotta Research Laboratorium S.p.A., Monza, Italy.

The Metabolism of Tumors in the Body
Otto Warburg, Franz Wind, and Erwin Negelein
The Journal of General Physiology Vol. 8, No. 6, Pg. 519-30 (1927)

Repairing Parchment With Collagen
Chris Woods
Conservation DistList Instance 10:89 cdl-10-89-005 (1997)

Effects of Collagen Peptide Ingestion on UV-B-Induced Skin Damage
M. Tanaka, Y. Koyama, Y. Nomura
Bioscience, Biotechnology, and Biochemistry Vol. 73, No. 4, P.g 930-32 (2009)


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